Publications Resulting from the RRNL

2010

• Reynolds HR, Buyon J, Kim M, Rivera TL, Izmirly P, Tunick P, Clancy RM. Association of plasma soluble E-selectin and adiponectin with carotid plaque in patients with systemic lupus erythematosus. Atherosclerosis. 2010 Jun;210(2):569-74. PMID: 20044088
• Karnabi E, Qu Y, Wadgaonkar R, Mancarella S, Yue Y, Chahine M, Clancy RM, Buyon JP, Boutjdir M. Congenital heart block: identification of autoantibody binding site on the extracellular loop (domain I, S5-S6) of alpha(1D) L-type Ca channel. J Autoimmun. 2010 Mar;34(2):80-6. PMID: 19640679
• Izmirly PM, Llanos C, Lee LA, Askanase A, Kim MY, Buyon JP. Cutaneous manifestations of neonatal lupus and risk of subsequent congenital heart block. Arthritis Rheum. 2010 Apr;62(4):1153-7. PMID: 20131261
• Friedman DM, Llanos C, Izmirly PM, Brock B, Byron J, Copel J, Cummiskey K, Dooley MA, Foley J, Graves C, Hendershott C, Kates R, Komissarova EV, Miller M, Paré E, Phoon CK, Prosen T, Reisner D, Ruderman E, Samuels P, Yu JK, Kim MY, Buyon JP.
• Evaluation of fetuses in a study of intravenous immunoglobulin as preventive therapy for congenital heart block: Results of a multicenter, prospective, open-label clinical trial. Arthritis Rheum. 2010 Apr;62(4):1138-46. PMID: 20391423
• Askanase AD, Izmirly PM, Katholi M, Mumtaz J, Buyon JP. Frequency of neuro-psychiatric dysfunction in anti-SSA/SSB exposed children with and without neonatal lupus. Lupus. 2010 Mar;19(3):300-6. PMID: 20008445
• Clancy RM, Marion MC, Kaufman KM, Ramos PS, Adler A; Slegen, Harley JB, Langefeld CD, Buyon JP. Genome-wide association study of cardiac manifestations of neonatal lupus identifies candidate loci at 6p21 and 21q22. Arthritis Rheum. 2010 Jul 26. PMID: 20662065
• Clancy RM, Alvarez D, Komissarova E, Barrat FJ, Swartz J, Buyon JP. Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block. J Immunol. 2010 Feb 15;184(4):2148-55. PMID: 20089705
• Briassouli P, Komissarova EV, Clancy RM, Buyon JP. Role of the Urokinase Plasminogen Activator Receptor in Mediating Impaired Efferocytosis of Anti-SSA/Ro-Bound Apoptotic Cardiocytes: Implications in the Pathogenesis of Congenital Heart Block. Circ Res. 2010 Aug 6;107(3):374-87. PMID: 20558828
• Buyon JP. Updates on lupus and pregnancy. Bull NYU Hosp Jt Dis. 2009; 67(3): 271-5. PMID: 19852749

 

2009

• Llanos C, Chan EKL, Li S, Abadal GX, Izmirly P, Byrne C, Clancy RM, Buyon JP.  Antibody reactivity to a-Enolase in mothers of children with autoimmune congenital heart block (CHB).  J Rheumatol 2009; 36: 565-9.  PMID: 19208599
• Friedman DB, Kim MY, Copel JA, Llanos C, Davis C, and Buyon JP. Prospective Evaluation of Fetuses with Autoimmune Associated Congenital Heart Block Followed in the PR Interval and Dexamethasone Evaluation (PRIDE) Study.  Am J Cardiol 2009; 103: 1102-6.  PMID: 19361597
• Buyon JP, Clancy RM, Friedman DM.  Cardiac manifestations of Neonatal Lupus: Guidelines to management integrating clues from the bench to bedside.  Nat Clinl Pract Rheumatol.  2009; 5: 139-148.  PMID: 19252519
• Buyon JP, Clancy RM, Friedman DM.  Autoimmune associated congenital heart block: Integration of clinical and research clues in the management of the Maternal/Fetal Dyad at risk.  J Internl Med 2009 Jun;265(6):653-62.   PMID: 19493059
• Llanos C, Izmirly PM, Katholi M, Clancy RM, Friedman DM, Kim MY, Buyon JP. Recurrence Rates of Cardiac Manifestations Associated with Neonatal Lupus and Maternal/Fetal Risk Factors. 2009; Arthritis Rheum 2009 Oct;60(10):3091-7. PMID: 19790064

2008

• Friedman DM, Kim MY, Copel JA, Davis C, Phoon CKL, Glickstein JS, Buyon JP, for the PRIDE investigators.  Utility of cardiac monitoring in fetuses at risk for congenital heart block: The PR Interval and Dexamethasone Evaluation (PRIDE) prospective study.  Circulation. 2008 Jan29; 117(4): 485-493.  PMID: 18195175
• Niewold TB, Rivera TL, Buyon JP, Crow MK.  Serum type I interferon activity is dependent on maternal diagnosis in anti-SSA/Ro positive mothers of Neonatal Lupus patients.  Arthritis Rheum 2008;58: 541-546.  PMID: 18240214
• Buyon JP, Clancy RM. Dying right to live longer: positing apoptosis as a link between maternal autoantibodies and congenital heart block.  Lupus. 2008;17:86-90.  PMID: 18250129
• Buyon JP, Brucato A, Friedman DM.  What’s in a name? Ann Rheum Dis 2008; 67: 732. PMID: 18408119
• Hamar B, Copel JA, Buyon JP.  Chapter 26: Common Autoimmune Disorders in Pregnancy.   In High Risk Obstetrics: The Requisites in Obstetrics and Gynecology.  Funai EF, Evans MI, Lockwood CJ (editors).  Philadelphia, PA: Elsevier 2008; 421-443. 
• Izmirly P, Kim M, Le P, Llanos C, Katholi M, Clancy R, Salmon J, Buyon J.  Decreased risk of anti-Ro/La associated congenital heart (CHB) in fetuses exposed to hydroxychloroquine (HCQ). [abstract] Arthritis Rheum 2008; 58(suppl): S810.
• Llanos C, Izmirly P, Katholi M, Edberg JC, Kimberly RP, Clancy R, Buyon J.  Pregnancy outcomes subsequent to a child with autoimmune associated congenital heart block (CHB) and associated fetal/maternal risk factors. [abstract] Arthritis Rheum 2008; 58(suppl): S873. (Presented at a Plenary Session during the 2008 national meeting of the American College of Rheumatology in San Francisco, CA.)
• Routsias J, Stea E, Geffrard L, Friedman D, Llanos C, Clancy R, Buyon J, Tzioufas AG.  Longitudinal evaluation of anti-La idiotypic antibodies in mothers enrolled in the PITCH Study. [abstract] Arthritis Rheum 2008; 58(suppl): S804.
• Strandberg L, Winqvist O, Sonesson SE, Mohseni S, Bremme, K, Buyon J, Julkunen H, Wahren-Herlenius M.  Antibodies to amino acid 200-239 (p200) of Ro52 as serologic markers for the risk of developing congenital heart block. Clin Exp Immunol.  2008; 154:30-7.  PMID: 18727629
• Rivera T, Izmirly P, Birnbaum BK, Byrne P, Brauth JB, Katholi M, Kim MY, Fischer J, Clancy RM, Buyon JP.  Disease progression in mothers of children enrolled in the Research Registry for Neonatal Lupus.  Ann Rheum Dis. 2008; [Epub ahead of print].  PMID: 18625627

2007

• Friedman DM, Rupel A, Buyon JP. Epidemiology, etiology, detection and treatment of autoantibody-associated congenital heart block in neonatal lupus.  Curr Rheumatol Rep 2007; 9:101-108.  PMID: 17502039
• Izmirly PM, Rivera TL, Buyon JP.  Neonatal lupus syndrome.  Rheum Dis Clin North. Am. 2007; 33:267-285.   PMID: 17499707
• Copel JA, Buyon JP, Hamar B. Rheumatic disease in pregnancy.  In High Risk Obstetrics: The Requisites. Evans, Funai (editors).  Philadelphia, PA: Elsevier.  2007; 421-443.
• Clancy RM, Zheng P, O’Mahony M, Izmirly P, Zavadil J, Gardner L, Buyon JP.  Role of hypoxia and cyclic AMP in the transdifferentiation of human fetal cardiac fibroblasts: implications for progression to scar in autoimmune-associated congenital heart block. Arthritis Rheum. 2007;56:4120-31.  PMID: 18050204

2006

• Buyon JP,Clancy RM.  Neonatal lupus.  In Dubois' Lupus Erythematosus, 7th edition.  Wallace DJ, Hahn BH, eds. 2006; pp.1058-1080.
• Askanase AD, Buyon JP. Neonatal lupus: Clinical perspectives. In Systemic Lupus Erythematosus: A Companion to Rheumatology. Tsokos GC, Gordon C, Smolen JS, eds. 2006; pp. 466-472.
• Clancy RM, Neufing PJ, Zheng P, O’Mahoney M, Nimmerjahn F, Gordon TP, Buyon JP. Impaired clearance of apoptotic cardiocytes linked to anti-SSA/Ro-SSB/La antibodies in pathogenesis of congenital heart block. J Clin Invest 2006; 116:2413-2422.  PMID: 16906225
• Buyon JP, Clancy RM. Antibodies to SSA/Ro and SSB/La: Potential mechanisms of tissue injury in neonatal lupus-congenital heart block. In Systemic Lupus Erythematosus: A Companion to Rheumatology. Tsokos GC, Gordon C, Smolen JS, eds. 2006; pp. 248-257.
• Bachmann MP, Bartsch H, Gross JK, Maier SM, Gross TF, Workman JL, James JA, Farris AD, Jung B, Franke C, Conrad K, Schmitz M, Buttner C, Buyon JP, Semsei I, Harley JB, Rieber EP. Autoimmunity as a result of escape from RNA surveillance. J Immunol. 2006; 177:1698-1707.  PMID: 16849479
• Askanase AD, Iloh I, Buyon JP. Hypothyroidism, anti-thyroglobulin and anti-thyroperoxidase antibodies in the pathogenesis of autoimmune-associated congenital heart block. J Rheumatol 2006; 33:2099-2100.  PMID: 17014028
• Stea EA, Routsias JG, Clancy RM, Buyon, JP, Moutsopoulos HM, Tzioufas AG.  Anti-La/SSB anti-idiotypic antibodies in maternal serum: A marker of low risk for neonatal lupus in an offspring.  Arthritis Rheum 2006; 54: 2228-2234.  PMID: 16802359

2005

• Buyon JP, Clancy RM.  Neonatal lupus: basic research and clinical perspectives.  Rheum Dis Clin North Am 2005 May: 31(2):299-313. PMID: 15922147
• Buyon JP.  A bedside perspective of neonatal lupus.  In Reproductive and Hormonal Aspects of the Systemic Autoimmune Diseases (Vol. 4, The Handbook of Systemic Autoimmune Diseases, Asherson R, ed.).  Elsevier: Amsterdam.  2005: pp. 95-100..
• Buyon JP, Askanase AD, Kim MY, Copel JA, Friedman DM.  On identifying an early marker for congenital heart block: when is a long PR interval too long?  Comment on the article by Sonesson et al. Arthritis Rheum. 2005; 52:1341-1342.  PMID: 15818705
• Kamel R, Eftekhari P, Clancy R, Buyon JP, Hoebeke J.  Autoantibodies against the serotoninergic 5-HT₄ receptor and congenital heart block: A reassessment.  J Autoimmun. 2005: 25:72-76.  PMID: 16009533
• Buyon JP, Clancy RM.  Autoantibody-associated congenital heart block:  TGF-β and the road to scar.  Autoimmun Rev 2005; 4:1-7.  PMID: 15652772
• Clancy RM, Buyon JP. Reply to letter [Ruffatti A, Favaro M, Cozzi F, Tonello M, Grava C, Lazzarin P, Milanesi O, Marson P, Balboni A, Brucato A. Anti-SSA/Ro-related congenital heart block in two family members of different generations: Comment on the article by Clancy et al.]  Arthritis Rheum. 2005; 52:1625-1626.
• Clancy RM, Buyon JP, Ikeda K, Nozawa K, Argyle DA, Friedman DM, Chan EKL. Maternal antibody responses to the 52-kd SSA/Ro p200 peptide and the development of fetal conduction defects. Arthritis Rheum 2005;52:3079-3086.  PMID: 16200587
• Neufing PJ, Clancy RM, Jackson MW, Tran HB, Buyon JB, Gordon TP.  Exposure and binding of selected immunodominant La/SSB epitopes on human apoptotic cells: an initiating event of tissue injury in congenital heart block. Arthritis Rheum 2005; 52:3934-3942.  PMID: 16320341
• Friedman DM, Buyon JP. Complete atrioventricular block diagnosed prenatally: anything new on the block? Ultrasound Obstet Gynecol. 2005;26: 2-3.  

2004

• Buyon JP.  Neonatal lupus syndrome.  In Systemic Lupus Erythematosus, 4th Ed.  Lahita R, ed.  Elsevier Academic Press: San Diego. 2004; pp. 449-484.
• Brucato A, Buyon JP.  Neonatal lupus syndromes: clinical features.  In Handbook of Systemic Autoimmune Diseases, Vol 1: The Heart in Systemic Autoimmune Diseases. Doria A, Pauletto P, eds.  Elsevier: Amsterdam.  2004; pp. 163-188.
• Buyon JP, Rupel A, Clancy RM.  Neonatal Lupus syndromes.  Lupus 2004; 13:705-712.  PMID : 15485109
• Buyon JP.  Congenital heart block in neonatal lupus: the clinical perspective.  (Proceedings of the XXVth Chilean Rheumatology Meeting) Rev Chil Rheumatol 2004;20:192-196.
• Tran HB, Cavill D, Buyon JP, Gordon TP.  Intravenous immunoglobulin and placental transport of anti-Ro/La antibodies: Comment on the letter by Kaaja and Julkunen.  Arthritis Rheum. 2004; 50:337-338.   PMID: 14730639
• Glickstein JS, Buyon J, Kim M, Friedman DM. The fetal Doppler mechanical PR interval: A validation study. Fetal Diagn Ther2004; 19:31-34. PMID: 14646414
• Gordon P, Rosenthal E, Simpson J, Sharland, Brucato A, Franceschini R, De Bosschere K, Meheus L, Meroni PL, Hughes GRV, Buyon J.  Anti-52KD Ro, anti-60KD Ro and anti-La antibody profiles in neonatal lupus.  J. Rheumatol. 2004; 31:2480-2487.  PMID: 15570655
• Clancy RM, Backer CB, Yin X, Chang MW, Cohen SR, Lee LA, Buyon JP.  Genetic association of cutaneous neonatal lupus with HLA class II and TNF-a:  Implications for pathogenesis.  Arthritis Rheum. 2004; 50:2598-2603.  PMID: 15334474
• Hu K, Qu Y, Yue Y, Boutjdir M.  Functional basis of sinus bradycardia in congenital heart block.  Circ Res. 2004; 94:e32-38.  PMID: 14963005
• Clancy RM, Kapur RP, Molad Y, Askanase AD, Buyon JP.  Immunohistologic evidence supports apoptosis, IgG deposition and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block.  Arthritis Rheum. 2004; 50:173-182.  PMID: 14730614
• Clancy RM, Buyon JP.  More to death and dying: Apoptosis in the pathogenesis of SSA/Ro-SSB/La-associated congenital heart block.  Rheum Dis Clin North Am 2004; 30:589-602.  PMID: 15261343
• Clancy RM, Buyon JP.  Autoimmune-associated congenital heart block: Dissecting the cascade from immunologic insult to relentless fibrosis.  Anat Rec A Discov Mol Cell Evol Biol. 2004; 280A(2):1027-1035.   PMID: 15368347

2003

• Buyon JP. Neonatal lupus. In Rheumatology, 3^rd Edn. Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH (eds).  Mosby, Edinburgh: 2003; 1381-1383.
• Buyon JP, Clancy RM.  Neonatal lupus: Review of proposed pathogenesis and clinical data from the U.S.-based Research Registry for Neonatal Lupus.  Autoimmunity 2003; 36:41-50.  PMID: 12765470
• Solomon DG, Rupel A, Buyon JP.  Birth order, gender and recurrence rate in autoantibody-associated congenital heart block: implications for pathogenesis and family counseling. Lupus 2003; 12:646-647.  (erratum Lupus 2003; 12:801).  PMID: 12945727
• Buyon JP, Clancy RM.  Neonatal lupus syndromes.  Curr Opin Rheumatol 2003; 15:535-541.  PMID: 12960477
• Buyon JP, Clancy RM. Maternal autoantibodies and congenital heart block: mediators, markers and therapeutic approach. Sem Arthritis Rheum 2003; 33:140-154.  PMID: 14671725
• Buyon JP, Friedman DM.  Autoantibody-associated congenital heart block: the clinical perspective.  Curr Rheumatol Rep 2003; 5:374-8.  PMID: 12967520
• Askanase AD, Clancy RM, Buyon JP.  [Feist E, Keitzer R, Gerhold K, Horvath L, Wahren-Herlenius M, Dorner T.  Development of systemic lupus erythematosus in a patient with congenital heart block.] Arthritis Rheum 2003; 48:2699. 
• Friedman DM, Duncanson LJ, Glickstein J, Buyon JP: A review of congenital heart block.  Images Paediatr Cardiol 2003; 16:36-48.
• Buyon JP, Rupel A, Clancy RM.  Congenital heart block: Do fetal factors fuel the fire from inflammation to fibrosis?  Lupus 2003; 12:731-734.  PMID: 14596420
• Clancy RM, Chan EKL, Chandrashekhar S, Buyon JP.  Does the cellular localization of antigens in or on apoptotic blebs influence the pathogenicity or benefit of cognate antibodies?  Comment on the article by Dieude et al.  Arthritis Rheum. 2003; 48:2080-2082.  PMID: 12847710
• Stevens AM, Hermes HM, Rutledge J, Buyon JP, Nelson JL.  Myocardial-tissue-specific phenotype of maternal microchimerism in neonatal lupus congenital heart block.  Lancet 2003; 362:1617-1623.  PMID: 14630442
• Friedman D, Buyon J, Kim M, Glickstein JS.  Fetal cardiac function assessed by Doppler myocardial performance index (Tei index). Ultrasound Obstet Gynecol 2003; 21:33-36.  PMID: 12528158
• Clancy RM, Backer CB, Yin X, Kapur RP, Molad Y, Buyon JP.  Cytokine polymorphisms and histologic expression in autopsy studies: Contribution of TNF-α and TGFβ1 to the pathogenesis of autoimmune-associated congenital heart block.  J. Immunol 2003; 171:3253-3261.  PMID: 12960355
• Clancy RM, Buyon JP.  Clearance of apoptotic cells: TGF-beta in the balance between inflammation and fibrosis. J Leukocyte Biol. 2003; 74:959-60.  PMID: 12960252
• Buyon JP, Clancy RM.  From antibody insult to fibrosis in neonatal lupus: the heart of the matter.  Arthritis Res Ther 2003; 5:266-269. PMID: 14680501
• Baron-Faust, Rita and Buyon, Jill P.  The autoimmune connection: Essential information for women on diagnosis, treatment and getting on with your life.  Contemporary Books, MacGraw-Hill Companies, 2003.

2002

• Askanase AD, Friedman DM, Dische MR, Dubin A, Starc T, Katholi MC, Buyon JP.  Spectrum and progression of conduction abnormalities in infants born to mothers with anti-SSA/Ro-SSB/La antibodies.  Lupus 2002; 11: 145-151.  PMID: 11999879
• Tran HB, Ohlsson M, Beroukas D, Hiscock J, Bradley J, Buyon JP, Gordon TP. Subcellular redistribution of La(SS-B) autoantigen during physiologic apoptosis in the fetal mouse heart and conduction system: a clue to the pathogenesis of congenital heart block. Arthritis Rheum. 2002; 46: 202-208. PMID: 11817591
• Tran HB, Macardle PJ, Hiscock J, Davill D, Bradley J, Buyon JP, Gordon TP. Anti-La (SS-B) antibodies transported across the placenta bind apoptotic cells in fetal organs targeted in neonatal lupus.  Arthritis Rheum. 2002; 46:1572-1579.  PMID: 12115188
• Buyon JP, Clancy RM.  Pathogenesis of congenital heart block: Autoantibody insult to fibrosis.  In From Proteomics to Molecular Epidemiology: Relevance of Autoantibodies. Report on the 6^th Dresden Symposium on Autoantibodies, Dresden, September 4-7, 2002 (Conrad K, Fritzler M, Meurer M, Sack U, Shoenfeld Y, eds.).  Berlin: Pabst Science Publishers.  2002: 314-327. 
• Martin V, Askanase AD, Lee LA, Katholi M, Buyon JP. Long term follow-up of children with neonatal lupus and their unaffected siblings. Arthritis Rheum 2002; 46:2377-2383.  PMID: 12355485
• Kanagasegar S, Cimaz R, Kurien BT, Brucato A, Scofield RH. Neonatal lupus manifests as isolated neutropenia and mildly abnormal liver functions.  J Rheumatol. 2002; 29:187-191.  PMID: 11824959
• Lee LA, Sokol RJ, Buyon JP. Hepatobiliary disease in neonatal lupus erythematosus: Prevalence and clinical characteristics in cases enrolled in a national registry. Pediatrics 2002; 109:E11. PMID: 11773579
• Buyon JP, Clancy R, Di Donato F, Miranda-Carus ME, Askanase AD, Garcia J, Qu Y, Hu K, Yue Y, Chan EK, and Boutjdir M.  Cardiac 5-HT₄ serotoninergic receptors, 52kD SSA/Ro and autoimmune-associated congenital heart block. J Autoimmunity 2002; 19: 79-86.  PMID: 12367562
• Buyon JP. Pregnancy in women with Sjogren’s: Neonatal Lupus.  The Moisture Seekers – Published by the Sjogren’s Foundation Inc. (Vol.20 No.3, March 2002).
• Rosenthal D, Friedman DM, Buyon J, Dubin A.  Validation of the Doppler PR interval in the fetus.  J Am Soc Echocardiogr 2002; 15: 1029-30.  PMID: 12221431
• Friedman DM, Rupel A, Glickstein J, Buyon JP.  Congenital heart block in neonatal lupus: The pediatric cardiologist’s perspective. Indian J Pediatr. 2002; 69:517-522.  PMID: 12139139
• Askanase AD, Miranda-Carus ME, Tang X, Katholi M, Buyon JP. The presence of IgG antibodies reactive with components of the SSA/Ro-SSB/La complex in human breast milk: implications in neonatal lupus. Arthritis Rheum. 2002;46:269-71.  PMID: 11817601

2001

• Buyon JP, Kim MY, Copel JA, Friedman DM.  Anti-SSA/Ro antibodies and congenital heart block: necessary but not sufficient.  Arthritis Rheum. 2001; 44:1723-1727.   PMID: 11508420
• Moak JP, Barron KS, Hougen TJ, Cohen MH, Nordenberg A, Van Hare GF, Perez, M, Cecchin F, Schneider DS, Nehgme RA, Buyon JP.  Congenital heart block: development of late-onset cardiomyopathy, a previously underappreciated sequela.  J Am Coll Cardiol. 2001; 37:238-242.  PMID: 11153745
• Wang D, Buyon JP, Yang Z, Di Donato F, Miranda-Carus ME, Chan EKL.  Leucine zipper domain of 52kDa SS-A/Ro promotes protein dimer formation and inhibits in vitro transcription activity.  Biochim Biophys Acta 2001; 1568: 155-161.  PMID: 11750763
• Restivo M, Kozhevnikov DO, Boutjdir M.  Optical mapping of activation patterns in an animal model of congenital heart block.  Am J Physiol Heart Circ Physiol 2001; 28: 1889-1895.  PMID: 11247806
• Xiao GQ, Hu K, Boutjdir M. Direct inhibition of expressed cardiac L- and T-type calcium channels by IgG from mothers whose children have congenital heart block. Circulation 2001; 103:1599-1604.  PMID: 11257091
• Qu Y, Xiao GQ, Chen L, Boutjdir M. Autoantibodies from mothers of children with congenital heart block downregulate cardiac L-type Ca channels. J Mol Cell Cardiol 2001; 33: 1153-1163.  PMID: 11444920
• Buyon JP.  Understanding the causes of CHB.  HJD Joint Talk-Employee News and Events.  April 2001; p3.
• Di Donato F, Chan EK, Askanase AD, Miranda-Carus M, Buyon JP. Interaction between 52 kDa SSA/Ro and deubiquitinating enzyme UnpEL: a clue to function. Int J Biochem Cell Biol. 2001; 33: 924-34. PMID: 11461834  

2000

• Buyon JP.  The heart and skin of neonatal lupus: does maternal health matter?  Am J Medicine 2000; 108:741-743.  PMID: 10924654
• Neiman AR, Lee LA, Weston WL, Buyon JP.  Cutaneous manifestations of neonatal lupus without heart block: characteristics of mothers and children enrolled in a national registry.  J. Pediatr. 2000; 37:674-680.  PMID: 11060534
• Miranda-Carús ME, Dinu Askanase A, Clancy RM, Di Donato F, Chou TM, Libera MR, Chan EKL, Buyon JP. Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of tumor necrosis factor a by macrophages. J Immunol 2000; 165:5345-5351.  PMID: 11046070
• Glickstein JS, Buyon JP, Friedman D. Pulsed Doppler echocardiographic assessment of the fetal PR interval. Am J Cardiol 2000; 86:236-239.
• Buyon JP.  Neonatal lupus.  Systemic Lupus Erythematosus in Clinical Practice 2000; 3:1-3. 

1999

• Brucato A, Buyon JP, Horsfall AC, Lee LA, Reichlin M.  Workshop report: Fourth International Workshop on Neonatal Lupus Syndromes and the Ro/SSA-La/SSB System.  Clin Exp Rheumatol 1999; 17:130-136.  PMID: 10084055
• Buyon JP.  Autoimmune-associated congenital heart block: bringing bedside challenges to the bench.  In Lupus: Cellular and Molecular Pathogenesis.  Kammer GM, Tsokos GC, eds.  Humana Press; Totowa, NJ. 1999; pp. 492-514.
• Buyon JP.  Congenital heart block: autoimmune associated or autoimmune mediated? The Immunologist 1999; 7:98-104.
• Saleeb S, Copel J, Friedman D, Buyon JP.  Comparison of treatment with fluorinated glucocorticoids to natural history of autoantibody‑associated congenital heart block: Retrospective review of the Research Registry for Neonatal Lupus. Arthritis Rheum. 1999; 42:2335-2345.  PMID: 10555029
• Wang D, Buyon JP, Zhu W, Chan EKL.  Defining a novel 75 kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies.  J Clin. Invest. 1999; 104:1265-1275.  PMID: 10545525
• Tseng CE, Miranda E, DiDonato F, Boutjdir M, Rashbaum W, Chan EKL, Buyon JP.  mRNA and protein expression of SSA/Ro and SSB/La in human fetal cardiac myocytes cultured using a novel application of the Langendorff procedure.  Pediatr. Res. 1999;45:260-269. PMID: 10022600

1998

• Buyon JP, Hiebert R, Copel J, Craft J, Friedman D, Katholi M, Lee LA, Provost TT, Reichlin M, Rider L, Rupel A, Saleeb S, Weston W, Skovron ML: Autoimmune-associated congenital heart block: Demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry.  J Am Coll Cardiol 1998; 31:1658-1666.  PMID: 9626848
• Boutjdir M, Chen L, Zhang ZH, Tseng CE, El-Sherif N, Buyon JP.  Serum and IgG from the mother of a child with congenital heart block induce conduction abnormalities and inhibit L-type calcium channels in a rat heart model.  Pediatr Res. 1998 Jul; 44(1): 11-9.
• Miranda-Carus ME, Tseng CE, Rashbaum W, Ochs RL, Casiano CA, DiDonato F, Chan EKL, Buyon JP.  Accessibility of SSA/Ro and SSB/La antigens to maternal autoantibodies in apoptotic human fetal cardiac myocytes.  J. Immunol. 1998;161:5061-5069.  PMID: 9794444
• Buyon JP.  Pregnancy in women with Sjogren’s Syndrome: neonatal problems.  In the New Sjogren’s Syndrome Handbook.  Oxford University Press, New York, 1998, pp. 134-139. 
• Buyon JP, Brucato A.  Neonatal lupus.  Seminars in Clinical Immunology 1998; 1:5-19.
• Buyon JP. Neonatal lupus syndrome.  In Systemic Lupus Erythematosus, 3rd Ed.  Lahita R, ed.  Academic Press.  1998; pp. 337-359.
• Friedman DM, Zervoudakis I, Buyon JP.  Perinatal monitoring of fetal well-being in the presence of congenital heart block.  Am. J. Perinatol 1998; 15:669-673.  PMID: 10333393
• Buyon, JP.  Neonatal lupus and autoantibodies reactive with SSA/Ro-SSB/La.  Scand. J. Rheumatol. 1998; 27(Suppl. 107):23-30. PMID: 9759127
• Miranda-Carús ME, Boutjdir M, Tseng CE, DiDonato F, Chan EK, Buyon JP. Induction of antibodies reactive with SSA/Ro-SSB/La and development of congenital heart block in a murine model. J Immunol. 1998; 161: 5886-92.  PMID: 9834068

1997

• Brucato A, Franceschini F, Buyon JP. Neonatal lupus: Long term outcomes of mothers and children and recurrence rate. Clin Exp Immunol 1997; 15:467‑473.  PMID: 9307852
• Buyon JP.  Autoantibodies reactive with SSA/Ro-SSB/La and pregnancy.  VI^th International Symposium on Sjögren's Syndrome, University of Connecticut, October 15-18, 1997.  J Rheumatol  Suppl. 1997 Sep; 50::12-6.  PMID: 9292829
• Tseng C, Buyon JP.  Neonatal Lupus Syndromes.  Rheum Dis Clin North America, 1997; 23:31-54.  PMID: 9031373
• Mayes MD, Giannini EH, Pachman LM, Buyon JP, Fleckman P.  Connective tissue disease registries.  Arthritis Rheum. 1997; 40:1556-1559.  PMID: 9324008
• Buyon JP, Tseng CE, Di Donato F, Rashbaum W, Morris A, Chan EK. Cardiac expression of 52beta, an alternative transcript of the congenital heart block-associated 52-kd SS-A/Ro autoantigen, is maximal during fetal development. Arthritis Rheum. 1997; 40: 655-60. PMID: 9125247
• Boutjdir M, Chen L, Zhang ZH, Tseng CE, DiDonato F, Rashbaum W, Morris A, el-Sherif N, Buyon JP. Arrhythmogenicity of IgG and anti-52-kD SSA/Ro affinity-purified antibodies from mothers of children with congenital heart block. Circ Res. 1997; 80:354-62.  PMID: 9048655

1996

• Buyon JP.  Neonatal lupus: Bedside to bench and back.  Scand J Rheum 1996; 25:271-276.  PMID: 8921918
• Buyon JP.  Neonatal lupus.  Curr Opin Rheumatol, 1996; 8:485-490.  PMID: 8941454
• Tseng CE, Caldwell K, Feit S, Chan EK, Buyon JP. Subclass distribution of maternal and neonatal anti-Ro(SSA) and La(SSB) antibodies in congenital heart block. J Rheumatol. 1996; 23: 925-32.  PMID: 8724310
• Tseng CE, Di Donato F, Buyon JP. Stability of immunoblot profile of anti-SSA/Ro-SSB/La antibodies over time in mothers whose children have neonatal lupus. Lupus. 1996; 5: 212-5.  PMID: 8803892